alienation
/ˌeɪlɪəˈneɪʃn; ˌelɪən`eʃən/ n [U] ~ (from sb/sth) alienating or being alienated; estrangement 疏远; 离间: His criminal activities led to complete alienation from his family. 他的犯罪活动导致了他与家庭完全隔绝. * Mental illness can create a sense of alienation from the real world. 精神病能产生一种与现实世界脱离的感觉.