alienate
alien·ate
/ˈeılijəˌneıt/ verb , -ates, -at·ed, -at·ing [ + obj ]
1 : to make (someone) unfriendly : to cause (someone) to stop being friendly, helpful, etc., towards you
He alienated most of his colleagues with his bad temper.
Her position on this issue has alienated many former supporters.
2 : to cause (someone) to feel that she or he no longer belongs in a particular group, society, etc.
— + from
Her position on this issue has alienated her from many voters.
His drug problems have alienated him from his parents.
alienated adj [more ~; most ~]
He feels very alienated from his parents.
alienated young people [=young people who do not feel that they have a part in society]
alien·ation /ˌeılijəˈneıʃən/ noun [ noncount ]
Her position on this issue has caused the alienation of many former supporters.
His alienation from his parents stems from his drug problems.
She has struggled with feelings of loneliness and alienation for much of her adult life.