adverse

ad·verse
 /ædˈvɚs, ˈædˌvɚs/  adj   [more ~; most ~]
  : bad or unfavorable : not good
   adverse criticism/remarks
   He had an adverse reaction to the medicine. [=he reacted badly to the medicine; the medicine had a bad effect on him]
   Many fear that budget cuts will have an adverse [=damaging] effect on education.
   adverse circumstances/conditions/weather
   The drug has no adverse [=harmful] side effects.
  ad·verse·ly  adv  
   Sales were adversely affected by the bad weather.
   Staff changes could affect the project adversely.

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